Estradiol Cream

Original price was: $45.00.Current price is: $36.00.

Embrace the power of balanced hormones with Estradiol Cream. 

Experience stronger bones and protection from osteoporosis, say goodbye to hot flashes and night sweats, and enjoy improved memory recall and increased libido.

Estradiol Cream also protects your heart by regulating cholesterol and triglyceride metabolism, reducing the risk of cardiovascular disease.

Estriol, the gentlest form of estrogen, is excellent for the skin and mucous membranes, making it ideal for combating vaginal dryness and reducing wrinkles. 

If for any reason you are not satisfied with your order, you will receive a full refund and prepaid packaging for the return.

SKU: EstradiolBigPump Category:
Estradiol is the strongest of the three estrogens your body makes and it has pros and cons.
Pros of Estradiol:  (when balanced with progesterone)
  • Important for bone health
  • Eliminating hot flashes and night sweats
  • Neuroprotective for the brain
  • Great for short-term memory and memory recall
  • Helpful for libido and sex drive
Cons of Estradiol:
  • Estradiol is mitogenic and likes to “grow things.”  (i.e. a fetus, grow the lining of uterus, which can cause a risk of uterine cancer)
  • Can cause spotting, bleeding, periods
  • Grow breast tissue
  • Cause breast tenderness
  • Enlarge breasts which can be a risk factor
  • Moody (weepy, irritable, anxious)
  • Can be similar to a 24/7 feeling of PMS
  • Weight gain

Many women report gaining on average 6 to 8 lbs when taking conventional estradiol hormone replacement.

So how do we get the positive benefits of estradiol without the negative side effects? The best way to properly balance estradiol is to take estriol and progesterone with it.


What's inside

This Vitamin E-based cream is packed with 1 mg of Natural USP Estradiol per pump and contains 99 pumps per bottle, making it easy to use. The combination of purified water, fractionated coconut oil, glycerine, and 5% Natural Vitamin E will hydrate and soothe your skin while delivering powerful benefits.


  • 1 ml contains 1 mg Bioidentical Estradiol and 25 IU Vitamin E.
  • 1/4 tsp contains 1.25 mg Estradiol and 9 IU Vitamin E.
  • Each ounce contains 28.4 mg of Estradiol and 2414 IU Vitamin E.
  • Soy, GMO, and Fragrance-Free.
  • Aspen Tree Bark Extract is a natural preservative.
  • This is a Vitamin E-based cream.
  • The airless pump bottle design protects the cream, keeping its contents fresh until needed.
  • Cream level strip on the back of the bottle, to know when you're getting low or are out of cream.



  • Increases libido
  • Improves memory recall
  • Reduces hot flashes
  • Reduces night sweats
  • Regulates cholesterol
  • Regulates triglyceride metabolism
  • Reduces risk of cardiovascular disease
  • Combats vaginal dryness
  • Reduces wrinkles


How to use

To ensure you receive the positive benefits of Estradiol without any negative side effects, it's recommended to combine it with estriol and progesterone. 

Estradiol Cream is easy to apply with fingertip application to the vaginal opening, delivering the estrogen directly to the area and helping to restore thickness and flexibility to the vaginal skin.

Pre-menopausal women should apply the cream daily for two weeks and then 2-3 times per week. Our airless pump bottle design protects the cream and keeps its contents fresh, and the cream-level strip on the back of the bottle lets you know when you're running low. 


Refund & Return Policy

If for any reason you are not happy with your order, you will get a full refund and you will be mailed prepaid packaging for the return.